Paramedic Mission

This is much more difficult than it would seem. A lot of experienced players will probably tell you, that the Paramedic mission is the hardets mission in the game. Personally, I don't know about that, but it's definitely one of them, so you should take it very seriously.

Get into an ambulance, and start picking up patients. Do this 12 levels in a row and you'll be able to sprint without tiring. Level one has one patient, level two has two patients and so on. I can't tell you exactly how to pass this mission, since there's no formula for success, but I can give you some general tips:

1. Always fill up your ambulance (three patients). Most of the time, delivering a full ambulance to the hospital will yield a time bonus.
2. Never ever approach a patient at full speed. Always reduce your speed a bit, and always brake well in advance. If you stop too soon, there's no harm done. If you stop too late, a lot of harm could be done!
3. Always apply your handbrake when using your normal brake for stopping by a patient. Once your ambulance is stopped, you won't begin moving backwards, if you have the handbrake applied, and you therefore won't back over a patient by accident.
4. There's ALWAYS enough time. Unless you're utterly hopeless behind the wheel, time should be of little concern to you. Besides, it will be reset every time you advance a level, meaning that you gain nothing if you deliver the final patient with 30 seconds left on the clock. If you drive too fast to shave off a second or two, chances are that you'll roll over your ambulance at one time or another.
5. If you slam into something, the patient(s) may start to moan a bit, and you'll be instructed to be careful. However, I've never had a patient die on me in the ambulance, so don't worry too much about it, although you should of course try not to hit every light post on the way to the hospital.
6. Rain isn't your friend. Reduce speed at all times if it's raining. The ambulance is no race car and it won't handle curves well if the roads are slippery. Also, remember that the roads will still be slippery a little after a rain shower. You're likely to encounter at least one rain shower while doing the paramedic mission.
7. Lack of concentration is your worst enemy! Never allow yourself to completely drift away. If you do, pause the game, get out your chair and do a few laps in your house/apartment.
8. Tipping over the ambulance is VERY easy, which I'm sure you'll learn on your first run. Try not to! If you sense that you're about to tip over, let off the accellerator and quickly turn TOWARDS the way you're about to tip over. Most people's first reaction is to turn "away from the tip", which would seem the logical thing to do, but unfortunately, what you do is to make sure the accident happens.
9. I tipped it over! I'm done for!
   Not so hasty, lad! The ambulance has a very special (and very unnatural) ability: you can actually lift the ambulance onto all four wheels again without even leaving the steering wheel. Turn towards the direction to which you have flipped and hit reverse. Watch as the ambulance miraculously pulls itself up again! Alright, what are you gawping at?? Get on with the mission!
10. Always look on your map when starting another level or even run. This way you can plot your route while the clock is stopped. Obviously, you should do the most economical / sensible route at all times, but if a shortcut is a little too packed with obstacles or dangerous curves, pick the safer route! As mentioned above, time should be of little concern to you once you know how to drive the ambulance.
11. If you hit something, do not despair. Concentrate on the next corner or obstacle ahead, and quit whining about something you can't do anything about. The ambulance is extremely durable, so unless you really drive stock car style, you won't smash up your ambulance before the 12 levels are completed. Having said that, you should obviously be careful about how you treat your ambulance.
12. Some people prefer the siren on, some don't. I for one prefer to have it on (even though the sound very soon gets a little tedious) for one reason only: most of the cars on front of you will get out of your way (or try to), and cars at intersections will slam on the brakes when they hear your siren wailing in the distance. The arrogant police, however, will not get out of the way, so be prepared. Remember that holding the horn-button will switch your siren to a higher pitch, and this will make cars hear you from a greater distance and they will try to get out of the way a little more vigorously. However, don't expect the difference to be huge, but by using this higher pitched siren on occasion, you can figure out what the other cars will do sooner. By the way: you needn't have your siren on for the patients to get in.
13. You needn't wait for your patients to get all the way in. As soon as they have opened the door, step on it! Don't worry, they always manage to get in.
14. The cardinal rule: Never EVER approach a patient head on. When your ambulance is close to a patient he/she will run towards your ambulance, and keep doing so provided that you don't drive too far away. If you're approaching them head on and hit the brakes a little too late, you will hit the patient and if you're going fast enough: road kill! Believe me - flattening a patient after 45 minutes of playing gives a new meaning to the word frustration! Always keep well to the left or right of the patient. If you overshoot, you won't run over the patient and he/she will automatically run up to your ambulance anyway.

Reward: After level 12, you will never get tired regardless of how long you sprint.